Here are the 55 US AI startups that have raised $100 million or more in 2025 | TechCrunch

The AI ​​industry entered 2025 with strong momentum.

There was 49 Startups That Raised Funding Rounds Worth $100 Million or more in 2024, according to our counts on TechCrunch; three companies raised more than one “mega round” and seven companies raised rounds equal to or greater than $1 billion.

The industry hasn’t slowed down in 2025. While fewer companies raised rounds above $1 billion, four — Anthropic raised two rounds over $1 billion — many more companies raised multiple rounds compared to 2024, eight.

How will 2026 compare? Elon Musk’s xAI announced a $20 billion Series E round and Sam Altman’s brain-computer interface startup Merge Labs raised a $250 million funding round (with OpenAI as lead investor) in the first weeks of 2026, so the signs point to another strong year. Of course, it’s still early; we will monitor whether the momentum continues.

Here are all the US AI companies that raised $100 million last year:

December:

• Based in Austin, Texas Mythicalwhich builds energy-efficient calculations for AI, raised a question $125 million funding round which was run by DCVC. The round was announced on December 17 and included, among other investors, SoftBank, NEA and Linse Capital.

• Chai Discovery announced a $130 million Series B round on December 15. The round valued the company that builds AI models for biotechnology and drug discovery at $1.2 billion. Oak HC/FT and General Catalyst co-led the tour.

• Generative Media Platform Fal announced its third funding round of 2025 on December 9. $140 million Series D funding round was led by Sequoia and valued the company at over $4.5 billion.

• Unconventional AI announced a monster funding round of $475 million led by Lightspeed Venture Partners and Andreesen Horowitz on December 8. The round valued the year-old startup, which is rethinking the foundations of computers in the AI ​​era, at nearly $4.5 billion.

• Based in Boston 7AI, which builds AI cybersecurity agents, raised a $130 million Series A round this was announced on December 4. Index Ventures led the round with participation from Greylock, Spark Capital and CRV, among others.

November

• All-in-one AI workspace platform Genspark announced a $275 million Series B round which valued the company at $1.25 billion on November 20. The round included Emergence Capital Partners, SBI Investment and LG Technology Ventures, among others.

• Advanced AIwhich builds models used for photo and video creation, raised $900 million in Series C funding round which valued the startup at $4 billion. The round was led by Humain with participation from Andreessen Horowitz, AMD Ventures and Amplify Partners, among others.

• Any spherethe creator of the viral mood coding platform Cursorraised $2.3 billion in funding round which valued the company at $29.3 billion. The funding round was announced on November 13 and is the company’s second funding round this year.

• Parallelwhich builds web infrastructure for AI agents, raised a $100 million Series A round this was announced on November 12. The round was co-led by Index Ventures and Kleiner Perkins.

• Starting an AI agent for the healthcare sector Hippocratic AI raised a $126 million Series C round which valued the company at $3.5 billion. This funding round, the second of the year for the company, was announced on November 3 and was led by Avenir Growth.

October

• Fireworks AIa platform that allows users to create AI applications using open source models, has raised a question $250 million Series C round this was announced on October 28. The round valued the company at $4 billion.

• Getting Started with Enterprise AI Uniphore is valued at $2.5 billion after a $260 million Series F round this was announced on October 22. The round included Snowflake Ventures, Nvidia, Databricks Ventures and AMD, among others.

• Sesamea voice AI company, raised a $250 million Series B round co-led by Sequoia and Spark Capital. The round was announced on October 21 and also included SignalRank as a participant.

• Based in Cambridge, Massachusetts OpenEvidencewhich is building an AI chatbot for the medical field, raised its second round of funding in 2025. $200 million Series C round was announced on October 20 and values ​​the company at $6 billion.

• Lila Scienceswhich seeks to build a scientific superintelligence platform, announced its second round of funding for 2025 on October 14. $350 million Series A round was co-led by Braidwell and Collective Global.

• DeepSeek Competitor Reflection AI announced its second mega-tour of the year on October 9. $2 billion Series B round valued the company at $8 billion and was led by Nvidia.

• Even Up, which is building AI for the personal injury legal field, announced a $150 million Series E funding round which valued the company at more than $2 billion on October 7. The round was led by Bessemer with participation from Lightspeed, Bain Capital and SignalFire, among others.

September

• Periodic laboratories, which builds an AI scientist, announced a $300 million funding round on September 30. Felicis and Andreessen Horowitz led the round with participation from Nvidia, Lightspeed and Khosla Ventures, among others.

• Brain systemsan AI infrastructure company, has raised a considerable sum $1.1 billion Series G round which valued the company at $8.1 billion. The funding round was announced on September 30 and was co-led by Fidelity and Atreides Management.

• Modular announced a A round of funding of 250 million dollars September 24. The round was led by the US Innovative Technology Fund with participation from GV, Greylock and General Catalyst, among others.

• Disstyle aiwhich develops enterprise AI software, raised a $175 million Series B round this was announced on September 23. This round valued the startup at $1.8 billion and included investors like Khosla Ventures and Lightspeed.

• Starting an AI infrastructure High-end AI raised a considerable amount $100 million funding round which was co-led by Maverick Silicon and Mayfield. The round was announced on September 17 and also included StepStone Group, Stanford University and Qualcomm Ventures, among others.

• Grokan AI inference company, raised a $750 million Series D-3 funding round which valued the company at nearly $6.9 billion. The round was announced on September 17 and was led by Disruptive.

• AI training startup Invisible technologies was valued at $2 billion after a A $100 million fundraiser this was announced on September 16. The raise was led by Vanara Capital with participation from Greycroft, Tallwoods Capital and Freestyle Capital, among others.

• Cognitive AIthe creator of the mood coding agent Devin, raised a $400 million Series C round this was announced on September 8. The round was led by Founders Fund and valued the company at $10.2 billion.

• Getting started with AI infrastructure The basset hound raised a $150 million Series D funding round which valued the company at $2.1 billion. The September 5 round was led by Bond with participation from CapitalG, IVP and Spark Capital, among others.

• Bret Taylor Customer Service AI Agent Platform Sierra raised $350 million in a round led by Greenoaks Capital. This fundraising was announced on September 4 and values ​​Sierra at more than $10 billion.

• You.coman AI-powered personalized search engine, has raised a $100 million Series C round led by Cox Enterprises. The funding round was announced on September 3 and values ​​the company at $1.5 billion.

• The Anthropic AI research laboratory raised its second round of funding for 2025 in September. Anthropic announced a $13 billion Series F round on September 2, this valued the company at $183 billion. The round was led by Iconiq, Fidelity and Lightspeed.

August

• Healthcare and Housing Automation Platform EliseAI raised $250 million in a Series E funding round that valued the startup at $2.2 billion. The cycle, announced on August 20, was directed by Andreessen Horowitz.
• Deviationan AI research laboratory, raised 100 million dollars at a valuation of $3.1 billion. The round included Sequoia Capital, Benchmark and Zeev Ventures and was announced on August 7.

July

• Generative Media Platform Fal raised a $125 million Series C round led by Meritech Capital Partners. The company announced the round July 31, which values ​​Fal at $1.5 billion. Salesforce Ventures, Shopify Ventures, Google AI Futures Fund and others joined the round.
• Five years Healthy atmospherewhich is building an AI healthcare operating system, raised a question $243 million Series C round which was led by Oak HC/FT and Andreessen Horowitz. Kleiner Perkins, OpenAI Startup Fund, Smash Capital and others also participated in the round.
• Delicious AIan AI research laboratory, raised $110 million in a round that included Snowflake and Nvidia. The Series B round was announced on July 22 and values ​​the company at $1 billion.
• AI Research Laboratory Thinking Machine Laboratory confirmed that he raised $2 billion on July 15. This important seed round was led by Andreessen Horowi tz with the participation of Nvidia, Accel and AMD, among others. The round values ​​the company at $12 billion.
• Based in Cambridge, Massachusetts OpenEvidencewhich is building an AI-powered research tool for clinicians, raised $210 million for a valuation of $3.5 billion. The Series B round was announced on July 15 and was led by Kleiner Perkins and GV.
• Harmonicwhich builds a mathematical reasoning engine, raised a $100 million Series B round directed by Kleiner Perkins. The funding round was announced on July 10 and values ​​the company at $875 million.

June

• AI unicorn in healthcare Shorten announced that it had raised a $300 million Series E funding round that values ​​the company at $5.3 billion. The round was led by Andreessen Horowitz with participation from Khosla Ventures. This was the company’s second round in 2025.
• Harveywhich develops AI tools for the legal sector, announced raised its second funding round of $300 million in 2025 on June 23. This latest Series E funding round was co-led by Kleiner Perkins and Coatue and brings the company’s valuation to $5 billion.
• Healthcare AI startup Ten No. announced that it had raised a $101 million Series C round led by IVP with participation from Lightspeed Venture Partners, GV and Andreessen Horowitz, among others. The round values ​​the company at $605 million.
• Starting Business Search Glean continues to raise money. The company announced a $150 million Series F round on June 10, led by Wellington Management with participation from Sequoia, Lightspeed Venture Partners and Kleiner Perkins, among others. Glean is now valued at $7.25 billion.
• Any spherethe AI ​​research lab behind AI coding tool Cursor, has raised a considerable sum $900 million Series C round that values ​​the company at nearly $10 billion. The round was led by Thrive Capital with participation from Andreessen Horowitz, Accel and DST Global.

Can

• Getting started with AI data labeling Snorkeling AI announced a $100 million Series D funding round on May 29, valuing the company at $1.3 billion. The round was led by Addition with participation from Prosperity7 Ventures, Lightspeed Venture Partners and Greylock.
• LMAa popular and community-based benchmarking tool for AI models, raised a question $100 million funding round which valued the startup at $600 million. The round was announced on May 21 and was co-led by Andreessen Horowitz and UC Investments. Lightspeed Venture Partners, Kleiner Perkins and Felicis also participated, among others.
• Las Vegas-based AI infrastructure company TensorWave announced a $100 million Series A round on May 14. The round was co-led by Magnetar Capital and AMD Ventures with participation from Prosperity7 Ventures, Nexus Venture Partners and Maverick Silicon.

April

• SandboxAQ closed one $450 million Series E funding round on April 4, which valued the AI ​​model company at $5.7 billion. The round included, among other investors, Nvidia, Google and Bridgewater Associates founder Ray Dalio.
• Trackwhich creates AI models for media production, raised a question $308 million Series D funding round this was announced on April 3, valuing the company at $3 billion. It was led by General Atlantic. SoftBank, Nvidia and Fidelity also participated.

March

• An AI giant OpenAI raised a record A round of funding of 40 billion dollars which valued the startup at $300 billion. This round, closed on March 31, was led by SoftBank with participation from Thrive Capital, Microsoft and Coatue, among others.
• On March 25, AI Nexthopan AI infrastructure company, announced that it has raised a Series A funding round led by Lightspeed Venture Partners. THE $110 million funding round also included Kleiner Perkins, Battery Ventures and Emergent Ventures, among others.
• Based in Cambridge, Massachusetts Insilico Medicine raised $110 million for its generative AI-based drug discovery platform, as announced on March 13. This Series E round valued the company at $1 billion and was co-led by Value Partners and Pudong Chuangtou.
• AI infrastructure company Celestial AI raised a $250 million Series C round which valued the company at $2.5 billion. The March 11 round was led by Fidelity with participation from Tiger Global, BlackRock and Intel CEO Lip-Bu Tan, among others.
• Lila Sciences raised a $200 million funding round as it seeks to create a scientific superintelligence platform. The cycle was led by Flagship Pioneering. The Cambridge, Massachusetts-based company also received funding from March Capital, General Catalyst and ARK Venture Fund, among others.
• Based in Brooklyn Reflection.Aiwhich seeks to build superintelligent autonomous systems, has raised a question $130 million Series A round that values ​​the year-old company at $580 million. The round was led by Lightspeed Venture Partners and CRV.
• Getting started with AI coding Turing closed a Series E round on March 7 that valued the startup, which partners with LLM companies, at $2.2 billion. THE $111 million funding round was led by Khazanah Nasional with participation from WestBridge Capital, Gaingels and Sozo Ventures, among others.
• AI Shieldan AI defense technology startup, raised $240 million in a Series F round that closed on March 6. This round was co-led by L3Harris Technologies and Hanwha Aerospace, with participation from Andreessen Horowitz and the US Innovative Technology Fund, among others. The round valued the company at $5.3 billion
• AI research and language model big business Anthropic raised $3.5 billion in Series E funding round which valued the startup at $61.5 billion. The round was announced on March 3 and was led by Lightspeed with participation from Salesforce Ventures, Menlo Ventures and General Catalyst, among others.

FEBRUARY

• AI setwhich creates an open-source generative AI and AI model development infrastructure, raised a question $305 million Series B round which valued the company at $3.3 billion. The February 20 round was co-led by Prosperity7 and General Catalyst with participation from Salesforce Ventures, Nvidia, Lux Capital and others.
• AI infrastructure company Lambda raised a $480 million Series D funding round this was announced on February 19. The round valued the startup at nearly $2.5 billion and was co-led by SGW and Andra Capital. Nvidia, G Squared, ARK Invest and others also participated.
• Shortenan AI platform that transcribes patient-clinician conversations, was valued at $2.75 billion in a Series D round announced on February 17. $250 million funding round was co-directed by IVP and Elad Gil. Lightspeed, Redpoint and Spark Capital also participated, among others.
• Eudiean AI-powered legal technology company, has raised $105 million in Series A funding round led by General Catalyst. Floodgate, Defy Ventures and Everywhere Ventures also participated in the round in addition to other venture capital firms and numerous angel investors. The cycle ended on February 13.
• Getting started with AI hardware Support AI raised a $100 million Series B round which also closed on February 13. The round was led by Tiger Global with participation from Scout Ventures, Samsung Ventures and RTX Ventures, among others. The Santa Clara-based company was founded in 2022.
• AI legal technology company Harvey raised a $300 million Series D round which valued the 3-year-old company at $3 billion. The round was led by Sequoia and announced on February 12. OpenAI Startup Fund, Kleiner Perkins, Elad Gil and others also participated in the raise.

January

• Synthetic voice start ElevenLabs raised a $180 million Series C round which valued the company at over $3 billion. This was announced on January 30. The cycle was co-directed by Iconiq and Andreessen Horowitz. Sequoia, NEA, Salesforce Ventures and others also participated in the round.
• Hippocratic AIwhich develops large language models for the healthcare sector, announced a $141 million Series B round on January 9. This funding round valued the company at over $1.6 billion and was led by Kleiner Perkins. Andreessen Horowitz, Nvidia and General Catalyst also participated, among others.

This article was updated on April 23, June 18, August 27, November 26, and January 19, 2026 to include more deals.

This article has been updated to remove the fact that Abridge is based in Pittsburgh; the company was founded there.

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