Men’s First Round Odds 2025-26: Spreads and Lines for All 32 Matches

Let’s get down to business. Check out the odds for every game in the first round of the men’s NCAA Tournament on DraftKings Sportsbook beginning March 20. This page may contain affiliate links to legal sports betting partners. If you register or place a bet, FOX Sports may be compensated. Learn more about sports betting on FOX Sports. THURSDAY, MARCH 19 No. 16 Siena 65, No. 1 Duke 71 Spread: Duke -28.5 (Siena covers) O/U: 136.5 (Under hits) No. 16 Howard 80, No. 1 Michigan 101 Spread: Michigan -30.5 (Howard covers) O/U: 151.5 (Over hits) No. 15 Idaho 47, No. 2 Houston 78 Spread: Houston -23.5 (Houston covers) O/U: 137.5 (under hits) No. 14 Kennesaw State 64, No. 3 Gonzaga 73 Spread: Gonzaga -21.5 (Kennesaw State covers) O/U: 152.5 (under hits) No. 14 North Dakota State 67, No. 3 Michigan State 92 Spread: Michigan State -15.5 (MSU coverages) O/U: 143.5 (on hits) No. 14 Penn 70, No. 3 Illinois 105 Spread: Illinois -25.5 (Illinois coverages) O/U: 151.5 (on hits) No. 13 Troy 47, No. 4 Nebraska 76 Spread: Nebraska -13.5 (Nebraska coverages) O/U: 139.5 (under hits) No. 13 Hawaii 78, No. 4 Arkansas 97 Spread: Arkansas -15.5 (Arkansas coverages) O/U: 158.5 (on hits) No. 12 High Point 83, No. 5 Wisconsin 82 Spread: Wisconsin -10.5 (HPU covers) O/U: 162.5 (on hits) No. 12 McNeese 68, No. 5 Vanderbilt 78 Spread: Vanderbilt -12.5 (McNeese coverages) O/U: 149.5 (on hits) No. 11 South Florida 79, No. 6 Louisville 83 Spread: Louisville -4.5 (USF coverages) O/U: 161.5 (on hits) No. 11 VCU 82, No. 6 UNC 78 (OT) Spread: UNC -2.5 (VCU coverages) O/U: 150.5 (on hits) No. 11 Texas 79, No. 6 BYU 71 Spread: BYU -2.5 (Texas coverages) O/U: 158.5 (on hits) No. 10 Texas A&M 63, No. 7 Saint Mary’s 50 Spread: Saint Mary’s -2.5 (A&M Covers) O/U: 148.5 (Under Hits) No. 9 TCU 66, No. 8 Ohio State 64 Spread: Ohio State -2.5 (TCU Covers) O/U: 146.5 (Under Hits) No. 9 Saint Louis 102, No. 8 Georgia 77 Spread: Georgia -2.5 (SLU covers) O/U: 168.5 (On hits) FRIDAY, MARCH 20 No. 16 LIU vs. No. 1 Arizona Spread: Arizona -30.5Moneyline: Arizona -100000, LIU +5000O/U: 149.5 No. 16 Prairie View vs. No. 1 Florida Spread: Florida -35.5Moneyline: Florida -100000, Prairie View +5000O/U: 155.5 No. 15 Tennessee State vs. No. 2 Iowa State Spread: ISU -24.5Moneyline: ISU -8000, Tennessee State +2200O/U: 148.5 No. 15 Queens U vs. No. 2 Purdue Spread: Purdue -25.5Moneyline: Purdue -8000, Queens U +2200O/U: 162.5 #15 Furman vs. No. 2 UConn Spread: UConn -20.5Moneyline: UConn -4500, Furman +1700O/U: 136.5 No. 14 Spread Wright State vs. Virginia No. 3 Spread: Virginia -18.5Moneyline: Virginia -2800, Wright State +1300O/U: 145.5 No. 13 Hofstra vs. No. 4 Alabama Spread: Alabama -11.5Moneyline: Alabama -800, Hofstra +550O/U: 158.5 No. 13 Cal Baptist vs. No. 4 Kansas Spread: Kansas -13.5Moneyline: Kansas -1350, Cal Baptist +800O/U: 138.5 No. 12 Akron vs. No. 5 Texas Tech Spread: Texas Tech -7.5Moneyline: Texas Tech -325, Akron +260O/U: 155.5 #12 Northern Iowa vs. #5 St. John’s Spread: St. John’s -9.5Moneyline: St. John’s -535, UNI +400O/U: 131.5 #11 Miami OH vs. #6 Tennessee Spread: Tennessee -11.5Moneyline: Tennessee -550, Miami OH +410O/U: 149.5 No. 10 Missouri vs. No. 7 Miami FL Spread: Miami -1.5Moneyline: Miami -130, Missouri +110O/U: 146.5 No. 10 Santa Clara vs. No. 7 Kentucky Spread: Kentucky -3.5Moneyline: Kentucky -155, Santa Clara +130O/U: 157.5 No. 10 UCF vs. No. 10. 7 UCLA Spread: UCLA -5.5Moneyline: UCLA -245, UCF +200O/U: 152.5 No. 9 Utah State vs. No. 8 Villanova Spread: Utah State -1.5Moneyline: Utah State -125, Villanova +105O/U: 146.5 No. 9 Iowa vs. No. 8 Clemson Spread: Iowa -2.5Moneyline: Iowa -130, Clemson +110O/U: 128.5