Oprah Winfrey has pushed back against allegations that her “very cautious walk” at Paris Fashion Week earlier this month was linked to her use of weight-loss drugs.
The media mogul has become one of the most talked about celebrities at the prestigious fashion event after returning to the catwalk circuit after several years away.
Oprah attended the show alongside longtime friend Gayle King, with the couple attracting attention for their stylish outfits and front-row appearance.
What really caught the audience’s attention, however, was Oprah’s noticeably slimmer figure and her slow, cautious gait upon arriving at the scene.
The moment quickly went viral online and sparked speculation about his continued use of GLP-1 weight loss drugs such as Ozempic.
Oprah Winfrey attracted attention with a careful walk at Paris Fashion Week
Footage from Paris Fashion Week went viral on social media after Oprah was seen arriving at the Chloé show in early March 2026.
A short clip of the moment spread on social media, showing the veteran journalist getting out of a car and taking small, careful steps toward the room.
The unusual walk immediately sparked debate online, with fans speculating about the possible reasons for the move.
On X, one user suggested it could be a combination of Oprah’s shoe choice and previous knee procedures.
“Oh, that’s why,” the user wrote. “She shouldn’t walk on heels after a knee replacement. That’s why she walks awesome.”
Fans Thought Ozempic Was Behind Oprah’s Viral March
Among the many theories circulating online about Oprah’s walk, one suggests it could be linked to her use of weight-loss drugs such as Ozempic.
“Ozempic ate her leg muscles,” one user said on X, while another asked, “What is going on here in Ozempic Oprah?”
The talk show icon first confirmed that she used weight management medication during an interview with PEOPLE in December 2023, just weeks before she turned 70.th birthday.
Oprah described the availability of clinically authorized weight loss treatments as a major breakthrough.
“The fact that there is a medically approved prescription to manage my weight and stay healthier throughout my life feels like a relief. Like redemption. Like a gift, not something to hide behind and be ridiculed again,” she said.
Oprah Winfrey explains the ’90s’ march
Oprah addressed the viral moment in a later interview, where she responded to online comments comparing her walk to that of a nonagenarian.
Behind-the-scenes footage of the conversation was posted to Instagram by a fan on Friday, then reposted by the billionaire channel itself.
Despite online theories about Ozempic, Oprah said the explanation for his walk was much simpler.
She clarified that she normally wore glasses or contact lenses and had difficulty seeing clearly upon entering the event.
“I didn’t know where I was walking, I couldn’t see,” she said, remembering repeatedly telling security: “I can’t see. Tell me where I’m walking.”
Oprah linked weight loss drugs to her sobriety
Two years after discussing her weight loss medications in an interview with PEOPLE, Oprah spoke with the outlet again in December 2025.
During the conversation, she revealed that sobriety had become an unexpected but welcome byproduct of treatment.
“I could [once] I drink more than everyone else at the table,” Oprah joked, reflecting on how much her habits have changed since she started taking the drug.
The media personality made the remarks while promoting “Enough: Your Health, Your Weight, and What It’s Like to Be Free,” a new book she co-authored with obesity expert Dr. Ania M. Jastreboff about the science behind weight and obesity.
Oprah Winfrey ‘gained 20 pounds’ when she stopped her weight-loss medication
Oprah says she learned an important lesson after briefly ditching her weight-loss medication.
Despite maintaining a healthy diet and workout routine, the entertainment icon said she gained about 20 pounds in the 12 months she went without treatment.
The experience came after Oprah suddenly decided to stop taking GLP-1 injections less than six months after she started using them.
“I tried to beat the medication,” she admitted.
Although some predicted she would gain weight back quickly after stopping treatment, Oprah said the pounds came back gradually but steadily.
This result finally convinced her that the drug might be necessary in the long term.
“It’s going to be the story of a lifetime,” she said.