Blake Shelton misses Gwen Stefani’s No Doubt Sphere opening night

Without a doubt, led by Gwen Stefanikicks off his Sphere residency in Las Vegas in a big way… but Blake Shelton won’t be there to see his lady light up the stage… TMZ has learned.

Sources with direct knowledge tell TMZ… Blake is taking time off and not by choice, but because he has his own gig at the exact same time. The country superstar is performing tonight at The Colosseum at Caesars Palace, down the street from Gwen.

Our sources say Blake is disappointed to miss opening night, but plans to attend the show during its run once his schedule clears up.

As for Gwen’s children… Kingston, Zouma And Apollo — they will also be absent this evening. We’re told it’s just a school night, and since classes are in session, they’re staying put for the time being. The plan is for them to attend a show later when they don’t have school the next day.

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We’re told the band has been rehearsing around the clock to perfect their visually immersive show at the Sphere, which is already generating huge buzz. The residency is a limited run until June 13, built specifically for the high-tech venue.