Anti-tick pill shows promising results in human trial

Enlarge Ladislav Kubes

If You to have A dog Or cat, odds are you have given your pet A fragrant to chew Tablet For tick prevention has a few indicate. What if You could take A similar pill has protect yourself Since get Lyme illness?

Tarsus Drugs East development such A pill For humans - less THE tasty aroma - that could provide protection against THE transmitted by ticks disease For several weeks has A time. In FEBRUARY, THE Irvine, Based in California biotechnology business announcement results Since A little, early stage trial showing that 24 hours After socket THE medicine, he can kill ticks on people, with THE effects sustainable For up has 30 days.

"What We consider East something that would be protect You Before THE tick would be even to bite You," said Police officer Azamien, CEO of Tarsus.

Lyme disease East A rapid growth issue In THE United States, Or approximately 476,000 people are diagnostic And treaty For he each year, according to has THE most recent data Since THE Centers For Disease Control And Prevention. That number East likely A overestimate, because a lot the patients are treaty After A tick to bite even if A infection is not it confirmed, but he underlines THE burden of Lyme disease on THE health care system - which researchers has THE CDC And Yale University put has almost $1 billion by year.

THE disease East cause by THE bacteria Borrelia burgdorferi, which gets pass has humans through THE to bite of A infected tick. In most case, A tick has has be attached For around 36 has 48 hours Before THE bacteria can be transmitted. Symptoms include fever, headache, fatigue, And A characteristic skin rash that looks as A target.

Without A vaccine For Lyme disease on THE walk, current prevention understand using insect repellents such as DEET And Permethrin And resistant farm shoes, long pants, And long sleeves When In A infested with ticks area.

" We have seen increasing rates of transmitted by ticks diseases on THE years, despite be said has TO DO tick checks, to use DEET, And to impregnate, to permeate your clothes with Permethrin, » said Paul Auwaerter, A teacher of medicine has THE Johns Hopkins University School of Medicine WHO studies Lyme illness.

A more effective treatment strategy would be be to welcome, Auwaerter said, especially because Lyme disease can Sometimes cause serious health problems. Antibiotics are generally effective When taken early, although about 5 has ten percent of the patients can to have persistent symptoms For weeks Or month. If LEFT untreated, THE infection can propagated has THE joints And cause arthritis. He can Also become established In THE heart And nervous system, provoking persistent fatigue, numbness, Or weakness.

THE experimental pill that Tarsus Drugs East essay East A formulation of lotilaner, A medicine that paralyzes And kill parasites by interfere with THE path that signals are pass between their nerve cells. Lotilaner East Already approved as A veterinarian medicine below THE brand name Credelio has control lice or fleas And ticks In dogs And cats.

"OUR animals to have better choice that We TO DO For tick prevention," said Linden Huh, A teacher of immunology has Tufts Medical School WHO directed THE Tarsus trial. "There are enough A little drugs And vaccines available For dogs And cats, but There is Nothing For We. »

Tarsus First of all developed lotilaner For human to use as A eye drop has to treat blepharitis, Or inflammation of THE eyelid, which East cause by tiny acarians. That medicine, Xdemvy, was approved by THE WE Food And Medicine Administration In July 2023. He stuns And kill mites here In THE eyelid. Azamien And her team had THE idea has test he against ticks In people. THE oral version of THE medicine enters THE blood And East pass has A tick When he bites And departures suction blood.

"A plot of drugs are tested In animals, but very little are commercialized For animated...